{"id":4258,"date":"2019-08-21T10:43:09","date_gmt":"2019-08-21T10:43:09","guid":{"rendered":"https:\/\/sportpaardenarts.nl\/?post_type=product&#038;p=4258"},"modified":"2026-11-06T15:58:59","modified_gmt":"2026-11-06T14:58:59","slug":"nebulin","status":"publish","type":"product","link":"https:\/\/sportpaardenarts.nl\/en\/shop\/for-the-airways\/to-nebulize\/nebulin\/","title":{"rendered":"Nebulin"},"content":{"rendered":"<p><strong>Nebulin<\/strong> is a powder containing a water-soluble turmeric extract (<em>Curcuma longa<\/em>), developed for nebulization in horses, for example with the <a href=\"https:\/\/sportpaardenarts.nl\/en\/shop\/brand\/nortev-flexineb\/flexineb-e3\/\">Flexineb nebulizer<\/a>. The product is used to support respiratory health, particularly in sport horses exposed to dust and other airborne irritants.<\/p>\n<p>Turmeric contains several biologically active compounds, including curcuminoids, which are known for their antioxidant and inflammation-modulating properties. Nebulin is dissolved in physiological saline solution before administration using a suitable equine nebulizer.<\/p>\n<h2>Properties and benefits<\/h2>\n<p>Nebulin contains a water-soluble extract of <em>Curcuma longa<\/em>. Its formulation allows the product to be administered through nebulization.<\/p>\n<p>According to the supplier, Nebulin is intended to provide additional respiratory support for horses that:<\/p>\n<ul>\n<li>Are regularly exposed to dust from hay, bedding, or the stable environment.<\/li>\n<li>Experience recurrent respiratory problems or coughing.<\/li>\n<li>Are subjected to increased respiratory demands during training or competition.<\/li>\n<li>Require additional respiratory support under veterinary supervision.<\/li>\n<\/ul>\n<p>The supplier also mentions its use in horses affected by exercise-induced pulmonary hemorrhage (EIPH). However, a clinically protective effect of Nebulin against EIPH has not been adequately demonstrated.<\/p>\n<h2>Scientific background<\/h2>\n<p>Curcumin, one of the main active compounds found in turmeric, has been investigated for its inflammation-modulating and antioxidant properties.<\/p>\n<p>An experimental study involving eight horses investigated the effects of inhaled water-soluble curcumin (NDS27) on experimentally induced neutrophilic airway inflammation. The researchers observed reductions in certain inflammation-associated enzymes, including myeloperoxidase and elastase, in bronchoalveolar lavage fluid. However, neutrophil counts did not decrease significantly.<\/p>\n<p>This study investigated a different curcumin formulation from Nebulin. Its findings therefore cannot be directly extrapolated to the clinical efficacy of Nebulin in horses.<\/p>\n<p><strong>Scientific publication:<\/strong> <a href=\"https:\/\/doi.org\/10.1186\/s40248-015-0010-7\" target=\"_blank\" rel=\"noopener\">Sandersen et al. (2015) \u2013 Effect of inhaled hydrosoluble curcumin on inflammatory markers in broncho-alveolar lavage fluid of horses with LPS-induced lung neutrophilia<\/a>.<\/p>\n<h2>Composition<\/h2>\n<p>Water-soluble turmeric extract (<em>Curcuma longa<\/em>).<\/p>\n<h2>Directions for use and dosage<\/h2>\n<p>Nebulin is supplied as a powder that must be dissolved in <a href=\"https:\/\/sportpaardenarts.nl\/en\/shop\/for-the-airways\/to-nebulize\/saline-nacl\/\">physiological saline solution<\/a> before use.<\/p>\n<p><strong>Preparation:<\/strong><\/p>\n<ol>\n<li>Measure 40 mL of sterile physiological saline solution (0.9% NaCl) suitable for inhalation.<\/li>\n<li>Add the saline solution to the vial containing 600 mg of Nebulin.<\/li>\n<li>Shake the vial thoroughly until the powder has dissolved.<\/li>\n<li>Transfer 6 mL of the prepared solution into the nebulizer chamber.<\/li>\n<li>Administer using a suitable equine nebulizer.<\/li>\n<\/ol>\n<p><strong>Recommended use:<\/strong> 6 mL per nebulization session, twice daily. According to the supplier&#8217;s protocol, Nebulin is administered for 3 days before and 3 days after a competition.<\/p>\n<p>At this dosage, one vial provides 3 days of use. Two vials are required for the complete 6-day protocol.<\/p>\n<p>Always follow the attending veterinarian&#8217;s individual recommendations regarding dosage, administration frequency, and duration of use.<\/p>\n<p>Do not nebulize Nebulin simultaneously with other products or mix it with other inhalation solutions or medications in the same nebulizer chamber.<\/p>\n<p><strong>Storage after preparation:<\/strong> According to the product information, the prepared solution can be stored for a maximum of 6 days at 4\u00b0C (39\u00b0F) in the refrigerator. Maintain appropriate hygiene during preparation and handling. Do not use the solution after the recommended storage period or if its microbiological safety can no longer be guaranteed.<\/p>\n<h2>Packaging and duration of use<\/h2>\n<p>Nebulin is available in a <strong>vial containing 600 mg of powder<\/strong>, which must be dissolved in 40 mL of physiological saline solution before use.<\/p>\n<p>At a dosage of 6 mL twice daily, one vial provides 6 complete nebulization sessions, equivalent to 3 days of use.<\/p>\n<p>Store the unopened product according to the instructions on the packaging. The prepared solution must be refrigerated.<\/p>\n<h2>Advice from the equine veterinarian<\/h2>\n<p>In sport horses, both inflammatory airway diseases and exercise-induced pulmonary hemorrhage (EIPH) can significantly affect performance. Although both conditions involve the respiratory system, their underlying mechanisms and treatment approaches differ.<\/p>\n<p>Nebulin contains a water-soluble turmeric extract and may be considered as an adjunct to support respiratory health under veterinary guidance. Research into inhaled curcumin provides an interesting scientific basis, but the clinical efficacy and safety of Nebulin itself have not yet been adequately established.<\/p>\n<p>In horses presenting with coughing, reduced performance, or suspected EIPH, I recommend a targeted respiratory examination. Depending on the clinical findings, post-exercise endoscopy, tracheal wash, or bronchoalveolar lavage may be indicated.<\/p>\n<p>Reducing exposure to dust and fungal spores remains essential in horses with inflammatory airway diseases. Nebulin does not replace targeted treatment of equine asthma or other respiratory conditions and should not be considered a proven preventive treatment for pulmonary hemorrhage.<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>Nebulin<\/strong> is a powder containing a water-soluble turmeric extract (<em>Curcuma longa<\/em>), developed for nebulization in horses. It is used as an adjunct to support respiratory health, particularly in sport horses regularly exposed to dust and other environmental irritants.<\/p>\n<p>Available in a <strong>600 mg vial<\/strong>, providing 3 days of use when nebulized twice daily.<\/p>\n","protected":false},"featured_media":11599,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[773],"product_tag":[],"class_list":["post-4258","product","type-product","status-publish","has-post-thumbnail","product_cat-to-nebulize","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nebulin for nebulization in horses | Sportpaardenarts<\/title>\n<meta name=\"description\" content=\"Nebulin with water-soluble turmeric extract for nebulization in horses. 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