{"id":66794,"date":"2026-10-19T10:21:53","date_gmt":"2026-10-19T08:21:53","guid":{"rendered":"https:\/\/sportpaardenarts.nl\/?post_type=product&p=66794"},"modified":"2026-10-20T04:04:55","modified_gmt":"2026-10-20T02:04:55","slug":"silvaplex-200","status":"publish","type":"product","link":"https:\/\/sportpaardenarts.nl\/en\/shop\/for-the-airways\/to-nebulize\/silvaplex-200\/","title":{"rendered":"SilvaPlex 200"},"content":{"rendered":"

SilvaPlex 200<\/strong> is an aqueous solution containing chelated silver at a concentration of 200 ppm (parts per million). Originally marketed as SilvaPlex Throat Spray, the product is also used for nebulization in horses, for example with a Flexineb nebulizer<\/a>.<\/p>\n

Silver compounds are known for their antimicrobial properties. Scientific laboratory studies have demonstrated that certain silver solutions can retain antibacterial and antiviral activity after nebulization. However, the clinical efficacy and safety of nebulized SilvaPlex in horses have not yet been adequately established.<\/p>\n

Properties and benefits<\/h2>\n

SilvaPlex contains chelated silver stabilized in an aqueous solution. The antimicrobial activity of silver depends on several factors, including its chemical form, concentration, exposure time, and the microorganism involved.<\/p>\n

SilvaPlex 200 contains a higher silver concentration than SilvaPlex 100<\/a>. However, this does not necessarily mean that the higher concentration is clinically more effective in horses.<\/p>\n

Scientific research<\/h2>\n

Dr. Thibault Frippiat has published two peer-reviewed studies as first author investigating the antimicrobial properties of nebulized silver nanoparticles.<\/p>\n

Antibacterial activity (2021)<\/strong><\/p>\n

An in vitro study published in the Journal of Equine Veterinary Science<\/em> investigated the bactericidal activity of silver nanoparticles against Streptococcus equi<\/em> subsp. zooepidemicus<\/em> and Actinobacillus equuli<\/em> subsp. equuli<\/em>. Both bacterial species showed susceptibility to silver nanoparticles. Antibacterial activity was also demonstrated after nebulization, with the observed effect depending on the silver concentration and bacterial species.<\/p>\n

Antiviral activity (2023)<\/strong><\/p>\n

A subsequent study published in Virology<\/em> investigated the virucidal activity of nebulized silver nanoparticles against equine herpesvirus type 1 (EHV-1) and murine norovirus. Nebulization resulted in a substantial reduction in EHV-1 infectivity. In contrast, no significant reduction in murine norovirus infectivity was observed after nebulization.<\/p>\n

Both studies were conducted under laboratory conditions. Their findings provide a scientific basis for further investigation of nebulized silver compounds but do not establish the clinical efficacy or safety of SilvaPlex 200 in horses.<\/p>\n

Scientific publications:<\/strong><\/p>\n